The small Cederberg town saw its Moravian Mission Station, clinic and town hall completely destroyed over the weekend.

The West Coast District Municipality indicated that 53 structures had been destroyed.

"The nation's thoughts go out to the people of Wupperthal who have suffered terrible personal losses alongside cultural assets that are of importance to all South Africans and especially Moravian congregations across the Western Cape," said Ramaphosa in a statement.

He said government departments would work with the community to bring relief to the area.

Ramaphosa also commended initiatives launched by different communities and organisations to assist Wupperthal residents.

The City of Cape Town's Wilfred Solomon-Johannes said emergency workers and ambulances from the provincial government had assisted the fire victims overnight.

He said the telecommunications infrastructure had been completely destroyed, leaving the community unable to communicate efficiently.

It is understood that the provincial disaster management centre will do an aerial assessment to determine the extent of the damage.

"That will be while health officials assist with the dispensing of medication, especially for the aged and frail care, as many of the people living in the Wupperthal town are old people," Solomons-Johannes added.

The South African Social Security Agency (Sassa) has been informed of the situation, in order to assist with the provision of clothes, tents and food.

"The assistance from neighbouring towns and municipalities of Clanwilliam, Piketberg, Vredenburg, Malmesbury (Swartland), Cederberg, Matzikama and Bergriver is much appreciated in attempts to bring the raging blaze under control," said Solomons-Johannes.

News24